Abstract: Rare and precious medicinal fungi have attracted much attention to theirs high application and commercial values.But they grew slowly,low yield and medicinal component were instable,hence their large-scale development and application became a problem.This review summarized the progress on the studies of rare and precious medicinal fungi in recent years,including theirs optimization method of fermentation parameters,kinetics of fermentation and metabolic regulation.In addition,some related problems and perspectives were also discussed.

Key words: rare and precious medicinal fungi, mathematical model, kinetics of fermentation, metabolic regulation