NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (7): 1132-1135.doi: 10.16333/j.1001-6880.2017.7.009

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Chemical Constituents of Pseudostellaria heterophylla

ZHANG Chun-li1,2,XU Guo-bo1,2,LIU Jun1,3,LIAO Shang-gao1,2,3,HE Xun2,4*   

  1. 1 School of Pharmacy,Guizhou Medical University,Guian New District 550025,China; 2 National Engineering Research Center of Miao‘s Medicines& Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education),Guiyang 550004,China; 3 The Key Laboratory of Optimal Utilization of Natural Medicinal Resources,Guizhou Medical University; 4 School of Medicine and Health Management,Guizhou Medical University,Guian New District 550025,China
  • Online:2017-07-29 Published:2017-08-11

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Abstract: To understand the chemical constituents of Pseudostellaria heterophylla for clarifying its pharmacological basis,different types of column chromatography (CC) including macroporous resin CC,silica gel CC,reversed phase C18 CC and Sephadex LH-20 CC were employed for their isolation and purification.As a result,ten compounds were isolated and structurally determined as 3-furanmethanol α-D-galactopyranoside (1),piceid (2),dihydroferulic acid methyl ester (3),benzoic acid (4),caffeine (5),thymidine (6),salicylic acid (7),dihydroferulic acid (8),adenosine (9) and heterophyllin B(10) on the basis of NMR and HRMS.1 was a new compound,and 2-7 were isolated from this plant for the first time.

Key words: Pseudostellaria heterophylla, chemical constituents, 3-furanmethanol &alpha, -D-galactopyranoside