Abstract: To provide the experimental basis for the formulation selection,process design and storage conditions,the stability of inclusion complex of Chr and  βglucan (Chr-β-glu) was investigated.The influences of temperate,light intensity,pH and different solvent on the stability of Chr-β-glu was evaluated by degradation rate equation.It showed that Chr-β-glu had anti-light stability and thermal stability.However,the complex degradation rate was increased at high pH level.Its stability was great influenced by different solvent. The stability of Chr-β-glu is closely related to light intensity,temperate,pH and solvent type.So it should be stored in low temperature,keep out in sun and should be used in low pH level.

Key words: Chrysophanol, yeast glucan complex, stability, degradative kinetics