NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (增刊1): 166-170. doi: 10.16333/j.1001-6880.2017.S.033

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Optimization of Extraction Conditions of Rosa laevigata Michx.Flavonoids

LIU Xiang-wen ,HOU Lin,CUI Qing-hua,CHEN Zhi,YUAN Qi,TIAN Jing-zhen*   

  1. College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China
  • Online:2017-08-02 Published:2017-08-02

Abstract: To optimize flavonoids extraction condition .With the sum of licorice,quercetin,kaempferol,apigenin as an indicator,response surface methodology was adopted to optimize flavonoids extraction condition by taking enzymatic hydrolysis temperature,pH and dosage.nzymatic hydrolysis temperature 51.21 ℃,pH 4.88,dosage 0.53 mg/mL,under this condition,the predicted value of flavonoids extraction was 25.78 μg/5g,and the test value was 25.55 μg/5g,.the optimal extraction condition were Stable and reliable.

Key words: Rosa laevigata Michx, flavonoids, response surface methodology, HPLC