Abstract: To investigate the chemical compositions of Adenosma buchneroides,the methanol and aqueous methanol extracts were obtained from its whole plant.The combined extracts were isolated and purified using D101 macroporous resin,silica gel,Sephadex LH-20 column chromatography and semi-preparative HPLC.One new and sixteen known compounds were obtained and their structures were identified,on the basis of modern spectroscopic data and literature data,as acetylmartynoside C (1),1,3,5-trimethoxybenzene (2),p-hydroxybenzoic acid methyl ester (3),p-hydroxybenzaldehyde (4),p-methoxybenzyl alcohol (5),coniferaldehyde (6),sinapaldehyde (7),indole-3-carboxaldehyde (8),indole-3-carboxylic acid (9),eugenol-β-D-glucopyranoside (10),syringaresinol-4-O-β-D-glucopyranoside (11),carvacrol-β-D-glucopyranoside (12),menthiafolic acid (13),(8R)-evofolin B (14),apigenin (15),4,4′-dihydroxydibenzyl ether (16),respectively.All of these compounds were isolated and identified from the genus Adenosma for the first time.

Key words: Adenosma buchneroides, chemical constituents, phenylpropanoids, phenolic acids