The Application of HepG2 Insulin Resistance Cell Model in the Evaluation of Bioactivities

doi:10.16333/j.1001-6880.2018.8.031

Abstract

Abstract: Insulin resistance is a multigene regulatory disease which also induced by multifactor.Researchers have established many kinds of insulin resistant cell model to clarify the mechanism of insulin resistance,including HepG2 cells which are a wide-accepted model cell.This review gives a detailed discussion on the research progress in establishment of insulin resistance HepG2cell model,as well as the evaluation of bioactivities in insulin resistance,providing a reference in improving insulin resistance.

Key words: HepG2, insulin resistance, cell model, evaluation of bioactivities

CLC Number:

SONG Hao,NIU Qing-chuan,LI Yu-ping1*. The Application of HepG2 Insulin Resistance Cell Model in the Evaluation of Bioactivities[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2018, 30(8): 1469-1475.

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The Application of HepG2 Insulin Resistance Cell Model in the Evaluation of Bioactivities

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