NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2018, Vol. 30 ›› Issue (9): 1558-1564. doi: 10.16333/j.1001-6880.2018.9.015

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Phenolic Constituents from Uncaria lancifolia

YANG Ling1,XIAO Chun-gui2,HAI Qing-shan3,JIN Ya-ju3,WANG Zi-ming1,WANG Yun1,WANG Kou1*,WANG Fei2*   

  1. 1School of Pharmacy and Yunnan Key Laboratory of Natural Medicine Pharmacology,Kunming Medical University,Kunming 650500,China; 2BioBioPha Co.,Ltd,Kunming 650201,China; 3School of Basic Medical Science,Yunnan University of Traditional Chinese Medicine,Kunming 650500,China
  • Online:2018-10-08 Published:2018-10-10

Abstract: Phytochemical investigation on the 95% ethanol extract of Uncaria lancifolia led to the isolation of 19 phenolic compounds,including epicatechin (1),catechin (2),cinchonain Ia (3),cinchonain Ib (4),cinchonain Ⅱa (5),cinchonain Ⅱb (6),procyanidin B2 (7),procyanidin B5 (8),procyanidin C1 (9),hedyotol D (10),(±)-lariciresinol (11),(+)-pinoresinol (12),9-O-(Z)-feruloyllariciresinol (13),9-O-(E)-feruloyllariciresinol (14),(+)-lyoniresinol 9′-O-glucoside (15),pomegralignan (16),scopoletin (17),cleomiscosin B (18) and hymexelsin (19).This is the first reporting for the chemical constituents of U.lancifolia.All compounds were obtained from this plant for the first time.Among them,ten compounds including 7-14,16 and 19 were isolated from Uncaria genus for the first time.

Key words: Uncaria lancifolia, phenolic compounds, proanthocyanidins, lignans, coumarins

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