NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2019, Vol. 31 ›› Issue (6): 1023-1029. doi: 10.16333/j.1001-6880.2019.6.016

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Chemical constituents from the fruits of Chukrasia tabularis and their anti-bacterial activity against Ralstonia solanacearum

LIU Hui1,2,LIU Shou-bai3,WANG Hao2,CHEN Hui-qin2,WANG Pei2,MEI Wen-li2,YANG Ke-jun1*,DAI Hao-fu2*   

  1. 1College of Agriculture,Heilongjiang Bayi Agricultural University,Daqing 163000,China; 2Key Laboratory of Biology and Genetic Resources of Tropical Crops,Ministry of Agriculture,Institute of Tropical Bioscience and Biotechnology,Chinese Academy of Tropical Agricultural Sciences,Haikou 571101,China; 3Institute of Tropical Agriculture and Forestry,Hainan University,Haikou 570228,China
  • Online:2019-06-26 Published:2019-06-26

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Abstract: In order to study the chemical constituents of Chukrasia tabularis,fifteen compounds were isolated from the ethanol extract of the fruits of Chukrasia tabularis by chromatographic methods.Their structures were identified as methyl gallate (1),ethyl gallate (2),gallic acid (3),ozoroalide (4),stigmast-4-en-6β-ol-3-one (5),phellochin (6),chukranin A (7),chisopanin M (8),21α,24α-methylmelianodiol (9),toonaciliatin K (10),21α,25-dimethylmelianodiol (11),odoratone (12),bourjotinolone A (13) hispidone (14),and phragmalin di-isobutyrate (15) by spectroscopic methods.Compounds 4~14 were isolated from the genus Chukrasia for the first time.All the compounds were assayed of the anti-bacterial activity against Ralstonia solanacearum by paper disco diffusion method.Among them,compounds 1,2,and 3 exhibited moderate inhibitory activity.

Key words: Chukrasia tabularis, fruits, chemical constituents, Ralstonia solanacearum

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