Abstract: 20(R)-ginsenoside Rg3 was one of the major active components of ginseng saponins and was mainly used in anti-tumor therapy.In recent years,the pharmacological effects of 20(R)-ginsenoside Rg3 had made continuous progress.It was important to pay attention to the pharmacological effects of 20(R)-ginsenoside Rg3,especially the protective effects on cardio-cerebrovascular diseases,immune function enhancement,anti-hypertrophic scar and anti-fatigue activities.In this article,we summarized the relevant literature on 20(R)-ginsenoside Rg3 at home and abroad,and discussed its pharmacological effects and molecular mechanisms,which provided a scientific basis for the further research.

Key words: 20(R)-ginsenoside Rg3, saponins monomer, pharmacologic effects, molecular mechanisms