NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2022, Vol. 34 ›› Issue (4): 699-712. doi: 10.16333/j.1001-6880.2022.4.018

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Research progress on chemical constituents,pharmacological activities and clinical application of Euphorbia kansui

MA Li1,2,MENG Xian-hua1,YANG Jun-li1*   

  1. 1CAS Key Laboratory of Chemistry of Northwestern Plant Resources,Lanzhou Institute of Chemical Physics (LICP),Chinese Academy of Sciences (CAS),Lanzhou 730000,China;2University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2022-04-29 Published:2022-04-29

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Abstract:

The dry root tuber of Euphorbia kansui T.N.Liou ex T.P.Wang(Euphorbia genus in Euphorbiaceae) is a unique Chinese herbal medicine in China.The main chemical constituents and active components of E. kansui are jatrophane diterpenes,ingenane diterpenes,euphane triterpenes and tirucallane triterpenes,which have many pharmacological activities such as anti-tumor,anti-virus,anti-inflammatory,insecticidal,antioxidant and immune system inhibition.This review comprehensively summarized 102 terpenes and 14 steroids and their structural characteristics,and systematically summarized the pharmacological activity,processing and clinical application of  E. kansui,in order to provide reference for clinical rational drug use,quality control,resource comprehensive utilization and development of  E. kansui.

Key words: Euphorbia kansui, diterpenes, triterpenes, pharmacological activity, clinical application

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