Eucommiae Folium is a traditional Chinese medicine included in the Chinese Pharmacopoeia and valued for their potential as a medicinal and edible herb.Modern research has shown that Eucommiae Folium contains various chemical components,including flavonoids,phenolic acids,lignans,and iridoids,which exhibit pharmacological activities such as antioxidation,blood pressure reduction,lipid-lowering,neuroprotection,and bone protection.At present,a large number of drugs,health products,and foods have been developed with Eucommiae Folium as the main drug or raw material,and have been applied in various fields such as medical treatment,chemical industry,and animal husbandry.This review summarizes the chemical components,pharmacological activities,and applications of Eucommiae Folium based on literature searches of domestic and foreign studies over the past 20 years,providing scientific evidence for future research and resource development.