NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2010, Vol. 23 ›› Issue (6): 949-951.

• Article • Previous Articles     Next Articles

Lignans from the Stem of Schima Surperba

XU Wen, ZHOU Guang-xiong*, YAO Xin-sheng   

  1. Institute of Traditional Chinese Medicine & Natural Products, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China

  • Received:2009-01-09 Online:2011-01-10 Published:2011-10-19

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Abstract:

In order to study the chemical constituents from the stems of Schima superba Gardn. et Champ, the chemical constituents were isolated and purified by chromatography on silica gel, Sephadex LH-20 column and HPLC. As a result, nine lignans were isolated and identified as syringaresinol (1), pinoresinol (2), lariciresinol (3), balanophonin (4), 3-acetoxymethyl-5-[(E)-2-formylethen-1-yl]-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrobenzofuran (5), 4,9-dihydroxy-3,5'-dimethoxy-4',7-epoxy-8,5'-neolignane-9'-yl acetate (6), dihydrodehydrodiconifery alcohol (7), isolariciresinol (8), and 1-(3,4-dimethoxy phenyl)-2-O-(2-methoxy-4-omegahydroxy propylphenyl)propane-1, 3-diol (9) on the basis of spectroscopic analysis. All these compounds were reported from this plant for the first time.

Key words: Schima superba, lignans, isolate, identify