Research on the Protection of Rosemary from the Lipid Peroxidation Damage of the Liver in the Exercise Rat

Abstract

Abstract:

This experiment objects were SD rats (♂). The exercise models was set up by the intensive endurance training. The effect of rosemary on the activity of alanine aminotransferase in the serum and the free radical metabolism in the liver of the rats trained with the intensive endurance was studied. The results displayed that rosemary could decrease the activity of alanine aminotransferase in the serum and increase it in the liver (P<0.05); It could also reinforce the activity of SOD，GSH-P_x，and CAT of the liver in the different level，of which the activity of SOD and CAT were increased remarkably in the calm or athletic behavior (P<0.05)，and the activity of Px-GSH were increased remarkably in the athletic behavior (P<0.05). In addition，the rosemary could reduce the content of MDA in the liver，but reduced not remarkably in the athletic behavior (P>0.05). The study concluded that the rosemary could reinforce the activities of antioxidases in the liver，relieve the injury of the lipid peroxidation caused by the intensive endurance training in the liver of rat. Moreover，the rosemary effected in the different extent on the activities of different antioxidases in the same state.

Key words: rosemary, the intensive endurance training, liver, the free radical metabolism, alanine aminotransferase

ZHANG Jing, XIONG Zheng-Ying. Research on the Protection of Rosemary from the Lipid Peroxidation Damage of the Liver in the Exercise Rat[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(2): 365-368.

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