NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2011, Vol. 23 ›› Issue (5): 870-873.

• Article • Previous Articles     Next Articles

Interaction of Chitosan-Co with Bovine Serum Albumin

LI Xiao-fang1*, FENG Xiao-qiang1, YANG sheng2, SU Zhong-xing3, FU Guo-qing4   

  1. 1College of Life Science and Chemistry Tianshui Normal University, Tianshui 741001, China; 2Dingxi Teacher's school, Dingxi 743000, China; 3Chemistry and Chemical Engineering College, Lanzhou University, Lanzhou 730000,China; 4Tianshui Traditional Chinese Medical Hospital, Tianshui 741001, China
  • Received:2009-12-10 Online:2011-10-25 Published:2011-09-26

Abstract: The interaction of chitosan-Co and bovine serum albumin was studied by ultraviolet spectrum and fluorescence spectrum. The results showed that the ultraviolet absorption intensity of BSA increased with the increasing of the concentration of chitosan-Co. Chitosan-Co strongly quenched the fluorescence of BSA and it was the static quenching. The binding constant (KA) of CS-Co with BSA at room temperature was 2.40×106.

Key words: chitosan-Co, bovineserum albumin, ultraviolet spectrum, fluorescence spectrum

CLC Number: