A New Drimane-type Sesquiterpenoid from Fermentation Broth of Fomitiporia punicata

Abstract

Abstract: The ethyl acetate extract of Fomitiporia punicata were separated and purified by silica gel,RP-18,Sephadex LH-20 column chromatography.Their structures were determined on the basis of physicochemical properties and spectroscopic analysis.Eleven compounds were isolated and identified as squalene (1),palmitic acid (2),linoleicacid (3),(22E,24R)-ergosta-7,22-dien-3β-ol (4),methyl linoleata (5),(22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (6),(22E,24R)-ergosta-5,7,22-trien-3β-ol (7),(22E,24R)-5α,8α-epidioryergosta-6,22-dien-3β-ol (8),2α-methoxyl-3β,9β-dihydroxyergosta-7,22-diene (9),3β,6β-dihydroxycinnamolide (10),(22E,24R)-ergosta-7,22-dien-3β,5α,6β-triol (11).Compound 10 was a new drimane-type sesquiterpenoid,named as 3β,6β-dihydroxycinnamolide,other compounds were isolated from Fomitiporia punicata for the first time.

Key words: Fomitiporia punicata, chemical constituent, sesquiterpenes, 3&beta, ,6&beta, -dihydroxycinnamolide

CLC Number:

R284.2

GUO Huai-yu1,2, LU Yun-de1,2, LI Zheng-hui2, WANG Gang1, LIU Ji-kai2*. A New Drimane-type Sesquiterpenoid from Fermentation Broth of Fomitiporia punicata[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(1): 6-10.

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A New Drimane-type Sesquiterpenoid from Fermentation Broth of Fomitiporia punicata

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