Abstract: Eight compounds were isolated from Saxifraga stolonifera (L.) Meerb.The compounds were identified by spectral analysis (MS、IR、¹H-NMR and ¹³C-NMR) as 3,4-dihydroxy benzoic acid (1),amber acid (2),betulinic acid (3),3,4-Dihydroxybenzoic acid methyl ester (4),5,7-Dthydroxychromone (5),Quercetin-3-O-β-L-rhamnopyranoside (6), Quercetin 5-O-β-D-glucopyranoside (7),1-O-β-D-glucopyranosyl-(2S,3S,4R,8E/Z)-2-［(2′R)-2′-hydroxytetracosanoylamino)］-8-octadecene-1,3,4-triol (8).In addition to compounds 1,2,7,other compounds were first isolated from Saxifraga stolonifera (L.) Meerb.Testing the compounds on PC-3 prostate cancer cells in vitro inhibition by MTT showed that compounds 6 and 7 had the certain inhibition to the PC-3 prostate anceer,the extracts and compounds were tested by plate diffusion method for the inhibitory effect of different strains.compound 2 on Bacillus subtilis had potential inhibition.

Key words: Saxifraga stolonifera (L.) Meerb., chemical constituent, anticancer activity, antibacterial activity