Abstract: Ten flavonoids were separated and purified from Oxytropis myriophylla (Pall.) DC.by silica gel column chromatography,Sephadex LH-20 and preparation HPLC,etc. Based on the spectral analysis,their structures were elucidated as 4,4′-dimethoxy-2′-hydroxychalcone (1),2′,4′-dihydroxy-4-methoxychalcone (2), 7,8-dihydroxyflavonone (3), 4,2′,4′-trihydroxychalcone (4),2′,4′-ihydroxydihydrochalcone (5),4′-hydroxy flavonone-7-O-β-D-glucoside (6),2′,4′-dihydroxychalcone (7), apigenin (8), apigenin-7-O-β-D-glucuronide (9) and 3′,7-dihydroxy-2′,4′-dimethoxyisoflavan (10).Compounds 1-9 were isolated from this plant for the first time.

Key words: Oxytropis myriophylla (Pall.) DC., flavonoid component, structural identification