NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (11): 1745-1748.

• Article • Previous Articles     Next Articles

One-pot Synthesis of N-dehydroabietyl-1,4-dihydropyridines under Solvent-free Condition

CAO Yu1,2, SHAO Yu1, WANG Jin-shou1, WEI Shi-yong1, SHI Bo-an1*   

  1. 1 School of Chemical and Environmental Engineering,Hubei University for Nationalities;2 Key Laboratory of Biological Resources Protection and Utilization of Hubei Province,Hubei University for Nationalities,Enshi 445000,China
  • Online:2014-11-29 Published:2014-12-18

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Abstract: A one-pot Hantzsch reaction between disproportionated rosin amine and 1,3-dicarbonyl compounds in the presence of aldehydes was carried out at 80 ℃.1,4Dihydropyridines were obtained in 75%-85% yields.Their structures were characterized by means of IR, 1H-NMR,MS and elemental analysis.

Key words: disproportionated rosin amine, 1,4-dihydropyridine, 1,3-dicarbonyl compound, solvent-free, one-pot reaction

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