Abstract: Alzheimer’s disease(AD)is a progressive neurodegenerative disease.The pathological process of AD is complex and still unclear.Currently,almost no effective drugs for AD are available.In recent years,more and more biologically active polysaccharides were discovered,which indicates that the polysaccharides will play some roles in different clinical therapy,even in AD treatment.Here we review the research progress of bioactive polysaccharides in neuroprotection and in the prevention and treatment of Alzheimer’s disease.

Key words: polysaccharides, bioactive substances, neuroprotection, Alzheimer&rsquo, s disease