NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (3): 318-323.

• Article • Previous Articles     Next Articles

Study on Antioxidant Activities of Traditional Chinese Medicines by Electron Paramagnetic Resonance Technique

ZHOU Li-fang1, ZHU Xiang1, ZHAO Hong-li1, LAN Min-bo1,2*, SHI Xin-mei2   

  1. 1 Shanghai Key Laboratory of Functional Materials Chemistry,East China University of Science and Technology; 2 Research Centre of Analysis and Test,East China University of Science and Technology,Shanghai 200237,China
  • Online:2014-03-29 Published:2014-12-08

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Abstract: In this study,electron paramagnetic resonance (EPR) technique was used to investigate the antioxidant activities of five traditional Chinese medicines (TCM),including rhubarb, Dracocephalum moldavica L.,lemongrass,mistletoe and seed of common peganum.The 1,1-diphenyl-2-picryl hydrazyl radical (DPPH), hydroxyl free radical and superoxide anion free radicals scavenging abilities of the five studied TCMs were investigated.The results indicated that the five studied TCMs all showed scavenging abilities against three free radicals,in which rhubarb exhibited the strongest activities.Its IC50 of scavenging DPPH and superoxide anion free radical were all less than 0.5 mg/mL and the IC50 of scavenging hydroxyl free radical was 1.892 mg/mL.

Key words: electron paramagnetic resonance, antioxidant activities, traditional Chinese medicine, free radical

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