Abstract: Nine compounds were isolated from the alcohol extract of the vinestems of Calotropis gigantea (L.) Dryand.Their structures were elucidated as (3β, 5α, 14β, 17α)-3,14-dihydroxypregnan-20-one (1), epoxyconiferyl alcohol (2),syringic acid ethyl exter (3),protocatechuic acid (4),gallic acid (5 ), 4-O-ethylgallic acid (6), β-sitosterol (7), stigmasterol (8),daucoster (9) using physico-chemical proterties and spectroscopic data.Compounds 1~6 were isolated from C.gigantea for the first time.

Key words: Calotropis gigantea (L.) Dryand., Calotropis R.Brown, Chemical constituents, Structure identification