Cyclopeptides from Immature Fruits of Citrus aurantium

NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (9): 1416-1420.

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Cyclopeptides from Immature Fruits of Citrus aurantium

PENG Wen-wen1,2, HUANG Mao-bo1, SONG Wei-wu1, TAN Ning-hua1*

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany,Chinese Academy of Sciences, Yunnan Kunming 650201, China; 2Jiangxi Key Laboratory of Natural Products and Functional Food,Jiangxi Agricultural University,Jiangxi Nanchang 330045, China

Online:2014-09-30 Published:2014-11-02

Abstract

Abstract: Seven cyclopeptides were isolated and purified from the immature fruits of Citrus aurantium L.by silica gel,Sephadex LH-20 and HPLC. Their structures were determined on the basis of spectroscopic data as Cyclo-(Leu¹-Ile²-Ala³-Thr⁴-Gly⁵-Thr⁶-Phe⁷) (Citrusin I) (1), Cyclo-(Gly¹-Leu²-Val³-Leu⁴-Pro⁵-Ser⁶) (2), Cyclo(Leu¹-Leu²-Pro³-Tyr⁴-Gly⁵-Ser⁶-Pro⁷) (Citrusin III) (3), Cyclo-(Gly¹-Gly²-Leu³-Leu⁴-Leu⁵-Pro⁶-Pro⁷-Phe⁸) (4),Cyclo-(Pro-Ala) (5), Cyclo-(Ala-Ile) (6), Cyclo-(Ala-Leu) (7). All compounds except 2 and 4 were isolated from this plant for the first time.

Key words: Rutaceae, Citrus aurantium, cyclopeptide

CLC Number:

PENG Wen-wen1,2, HUANG Mao-bo1, SONG Wei-wu1, TAN Ning-hua1*. Cyclopeptides from Immature Fruits of Citrus aurantium[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(9): 1416-1420.

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Cyclopeptides from Immature Fruits of Citrus aurantium

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