NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (1): 169-172. doi: 10.16333/j.1001-6880.2015.01.034

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Study on the Synthesis and Performance of 1-Deoxynojirimyc in Molecularly Imprinted Polymer Micro-Spheres via Precipitation Polymerization

LUO Meng-jun1*, DENG Feng-jun1, GUO Qiao-hong1, CHEN Zong-gao2, CHEN Bo3   

  1. 1 Yiyang Medical College,Yiyang 413000,China;2No.1 Middle School of Yiyang,Yiyang 413000,China;3Chemical Engineering of Hunan Normal University,Changsha 410081,China
  • Online:2015-01-31 Published:2015-02-12

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Abstract: The 1-deoxynojirimyc molecular imprinted polymer (MIP) microsphere was synthesized in this study.The influences of reaction conditions,including the category of solvent and reaction time on the morphology and adsorption properties of MIP microspheres were studied.1-deoxynojirimyc MIP microspheres were prepared by precipitation polymerization with 1-deoxynojirimyc as template and ethyleneglycol dimethacrylate (EGDMA) as cross-linker.The microspheres were characterized by static adsorption and scanning electron microscopy (SEM).The results showed the reaction time was 24 h,and acetonitrile was the solvent.The 1-deoxynojirimyc MIP microspheres were regular microspheres.The MIP microspheres showed high adsorption capacity and the partition N-methyl-1-deoxynojirimycin of the microspheres adsorbing 1-deoxynojirimyc was 2.26.It showed that 1-deoxynojirimyc MIP microspheres had specific adsorption and recognition capabilities to 1deoxynojirimyc molecules.

Key words: precipitation polymerization, molecular imprinted polymer, 1-deoxynojirimyc, microsphere

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