Comparison of Three Methods for Determination of Chondroitin Sulfate Sodium Shark

doi:10.16333/j.1001-6880.2016.11.015

Abstract

Abstract: The content of chondroitin sulfate sodium shark (CS) was separately evaluated by enzymatic-high performance liquid chromatography (E-HPLC),high performance liquid chromatography (HPLC) and cetylpyridinium chloride (CPC)-titration methods.After comparing and analyzing the detection results,it was found that E-HPLC method was not suitable for determining chondroitin sulfate sodium shark.Moreover,the content determined by CPC-titration method was higher than that of HPLC method.By contrast,HPLC was more suitable for determining of chondroitin sulfate sodium shark.

Key words: enzymatic-high performance liquid chromatography, high performance liquid chromatography, cetylpyridinium chloride-titration, chondroitin sulfate sodium shark

CLC Number:

R927.2

JIAO Guang-fei*. Comparison of Three Methods for Determination of Chondroitin Sulfate Sodium Shark[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(11): 1771-1776.

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Comparison of Three Methods for Determination of Chondroitin Sulfate Sodium Shark

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