Abstract: Class II bacteriocins produced by lactic acid bacteria have been regarded as novel and safe food bio-preservatives due to their broad antimicrobial spectrum and the special antimicrobial activity against Listeria monocytogenes.Though Class II bacteriocins have great potential on food industry,low production is one of the bottlenecks for their application.Quorum-sensing is a physiological behavior that bacterial cells communicate with each other,so as to perceive the concentration of signal molecules to regulate the expression of genes.It has been reported that Class II bacteriocins production was regulated by the Quorum-sensing system in lactic acid bacteria.In this study,the regulatory mechanism of Quorum-sensing and its influence on the biosynthesis of bacteriocins was reviewed,which would make a solid foundation for the study on the improvement of bacteriocins production regulated by Quorum-sensing system.

Key words: Quorum-sensing, lactic acid bacteria, bacteriocins, biosynthesis regulation