Abstract: In this study,the content of flavonol glycosides was used as an evaluation index to screen the six kinds of clarifying agent,including diatomite, gelatin, chitosan,101 juice clarifying agent,ZTC1+1 natural clarifier and activated carbon,single factor and orthogonal test were applied to optimize the clarifying condition of Ginkgo biloba extract.The results showed the optimal clarification condition of G.biloba extract were:gelatin as the clarifying agent,3 mL per 10 g crude drugs with 1% gelatin solution,6:1 (mL/g) as extraction concentration,5.5 as extraction pH,40 ℃ as extraction temperature.Gelatin can be used as a clarifying agent of G.biloba extract and it is stable and feasible.

Key words: chitosan, diatomite, gelatin, 101 juice clarifying agent, ZTC1+1 natural clarifier, activated carbon, flocculation clarifying agent, Ginkgo biloba