Abstract: To establish an HPLC fingerprint of Bacopa monnieri.And all data was analyzed by the SPSS statistical software.The common mode of HPLC fingerprint was established,and the cluster analysis was applied to study the HPLC fingerprint and Chemical pattern recognition.Similarity of7 batches of Bacopa monnieri was more than 0.9,and similarity of 3 batches was below 0.9,similarity and the result of cluster analysis had a certain relationship with collecting zone environment ofBacopa monnieri.The combination of fingerprint and chemical pattern recognition is an effective method for the quality control of traditional Chinese medicinal materials and can reflect the comprehensive information of Bacopa monnieri and provide the scientific experimental basis for evaluating Bacopa monnieri.

Key words: Bacopa monnieri, fingerprint, HPLC, cluster analysis