Abstract: One new compound,7-ethyoxy tangshenoside Ⅱ (1),along with 21 known compounds were isolated from Codonopsis pilosula.The known compounds were identified as tangshenoside Ⅱ (2),4-hydroxycinnamyl-O-β-D-glucopyranoside (3),juniperoside (4),2-phenylethyl-β-D-glucopyranoside (5),syringoside (6),ethylsyringin (7),(+)-isolariciresinol (8),lariciresinol (9),7R,8S-dihydrodehydrodiconiferyl alcohol (10),vitrifol A (11),sesquimarocanol B (12),4-hydroxycinnamate (13),protocatechuic acid methyl ester (14),trans-ferulic acid (15),para-hydroxy benzaldehyde (16),cis-ferulic acid (17),thymine (18),1-beta-L-xylofuranosylpyrimidine-2,4 (1H,3H)-dione (19),2,4-(1H,3H-Pyrimidinedione) (20),4-methoxybenzene-1,2-diol (21),and 5-hydroxymethyl-5H-furan-2-one (22),respectively,by spectroscopic methods.With exception of new substance (1),compounds 2-5,8-12,18 and 19 were isolated from this species for the first time.

Key words: Codonopsis pliosula, Campanulaceae, chemical constituents, phenylpropanoid glycoside, lignans