Abstract: Houttuynia cordata Leaf Polysaccharides (HCP) was isolated and purified by Toyopearl column chromatography.The composition and proportion of polysaccharides were analyzed by GC-MS.The in vitro antioxidant capacity (DPPH scavenging ability,chelating ability of Fe²⁺ and the reducing ability of potassium ferricyanide) were studied.The antibacterial effect and the minimum inhibitory concentration were tested.The results showed that polysaccharides (HCP1,HCP2,HCP3) had certain scavenging ability to DPPH,the chelating effect on Fe²⁺ and the reduction effect of potassium ferricyanide,and the effect intensity was HCP1> HCP2> HCP3;the bacteriostatic experiment showed that the inhibitory effect of HCP1 and HCP2 on Staphylococcus aureus was the strongest with MIC of 0.9375 mg/mL,and the inhibitory effect of HCP3 on S.aureus and E.coli was the most effective with MIC of 1.875 mg/mL.

Key words: Houttuynia cordata Leaf, polysaccharide, antioxidant, antibacterial