Antihyperglycemic Effect of Propolis and Its Molecular Mechanism:A Review

doi:10.16333/j.1001-6880.2017.6.028

Abstract

Abstract: Propolis is a kind of bee products with various biological activities and health functions.The antihyperglycemic effect is one of biological activities of propolis.In this article,the research progress on the antihyperglycemic effect of propolis as well as its main flavonoids and phenolic acid were summarized.The molecular mechanisms,including IRS-PI3K pathway,PPARs transcription factors,AMPK pathway and antioxidant,were also summarized aiming to provide references for the future research of biological activities and further applications of propolis.

Key words: propolis, flavonoids, phenolic acid, antihyperglycemic, molecular mechanism

CHENG Xiao-yu,ZHANG Jiang-lin,HU Fu-liang*. Antihyperglycemic Effect of Propolis and Its Molecular Mechanism:A Review[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2017, 29(6): 1070-1076.

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Antihyperglycemic Effect of Propolis and Its Molecular Mechanism:A Review

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