NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (8): 1362-1367. doi: 10.16333/j.1001-6880.2017.8.018

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Preliminary Screening for Antioxidant and Anti-Trichophyton mentagrophyte Activities of Different Polarity Extracts from Caragana korshinskii Kom.

ZENG Zhi1,2,XU Heng1,2,BAI Bo1*,WANG Hong-lun1,SUO You-rui1   

  1. 1 Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810008,China; 2 University of the Chinese Academy of Sciences,Beijing 100049,China
  • Online:2017-08-28 Published:2017-08-28

Abstract: In this study,the flowers,leaves,bark and root of Caragana korshinskii Kom.were separately extracted by ethanol.And then all the extracts were further fractionated by petroleum ether (Pe) and ethyl acetate (Et) in sequence.Those extracts were applied to screen the anti-oxidant and anti-fungal activities.The anti-oxidant activity was carried out by scavenging radicals of DPPH,ABTS,hydroxyl radical (·OH) and superoxide anion (O·2).Inhibition zone was employed to evaluate the anti-fungal activity of those extracts.The results suggested that compared with vitamin C (Vc) the flowers and leaves of C.korshinskii showed good anti-oxidant activity of scavenging radical of DPPH and ABTS,especially for their Et fractions.However,all parts of the extracts showed weaker activity of scavenging ·OH and O·2 than Vc (P < 0.001).Screening for anti-fungal activity,the results showed that the Et fraction of flowers,leaves and bark are antifungal of Trichophyton mentagrophyte to some extent,especially the bark.Moreover,the inhibition ratio can be up to 50% when the concentration of the Et fraction of bark collected in autumn.Those consequences turned out that flowers and leaves of C.korshinskii can be a potential and exploitative resource.

Key words: Caragana korshinskii Kom., antioxidant activity, Trichophyton mentagrophyte, screening activity