Abstract: Osmanthus fragrans has a long history of cultivation and research in China. The present studies about  O.fragrans  mainly focus on food processing,essential oil and concrete. In order to clarify the comprehensive utilization value of  O.fragrans, the extraction,isolation,identification and pharmacological activities of the non-volatile components of  O.fragrans  were summarized in this review. The non-volatile components in O.fragrans  include flavonoids, terpenes, lignans and phenylethanoids, etc Osmanthus extracts showed anti-inflammation, anti-bacteria,antioxidation, melanin synthesis-inhibition, cytotoxicity, anti-aging and other pharmacological activities.The study on the extraction methods and the active components can provide reference for the further development and utilization of  O.fragrans.

Key words: Osmanthus fragrans, non-volatile constituents0, extraction, pharmacological activity