Abstract: To further investigate the antidiabetic constituents from the root of Averrhoa carambola L.,nine compounds were isolated from the water extracts by series column chromatographies and their structures were identified as prismaconnatoside (1),tarennanosides A (2),(+)-catechin (3),fernandoside (4),7a-［(β-glucopyranosyl)oxy］-lyoniresinol (5),(+)-lyoniresinol 3α-O-β-D-glucopyranoside (6),(-)-lyoniresinol 3α-O-β-D-glucopyranoside (7),(-)-5’-methoxy-isolariciresinol 3α-O-β-D-glucopyranoside (8),and n-octane (9).Compounds 1,2,4,and 5 were isolated from Averrhoa carambola for the first time.Compound 3 was isolated from the root part of Averrhoa carambola for the first time.Some compounds were assayed for the α-glucosidase and DPP-IV inhibitory activities in vitro.Compound 1 showed α-glucosidase inhibitory activity.

Key words: root part of Averrhoa carambola L., chemical constituents, purification, structure elucidation, α-glucosidase inhibitory activity