NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2019, Vol. 31 ›› Issue (12): 2077-2081.doi: 10.16333/j.1001-6880.2019.12.009

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Isolation and structure identification of chemical constituents from the fruits of Akebiae quinata

JIN Hong-guang*,LIU Ke-yue,QU Wei-hong,LI Tong-jian, LIAO Liang,YU Jing-mou*   

  1. College of Pharmacy and Life Science,Jiujiang University,Jiujiang 332000,China
  • Online:2019-12-28 Published:2020-01-10

Abstract: To study the non-triterpenoid chemical constituents of the fruits of Akebiae quinata.Fourteen compounds were isolated and purified by various chromatography methods,including macroporous resin HP-20,Sephadex LH-20,silica gel column and RP-18 column.Their structures were identified by spectroscopic methods as tyrosol (1),caffeic acid (2),protocatechuic acid (3),p-hydroxybenzoic acid (4),ferulic acid (5),salidroside (6),hydroxytyrosol glucoside (7),trans-coniferin (8),syringin (9),calceolarioside B (10),3-O-caffeoylquinic acid (11),4-O-caffeoylquinic acid (12),5-O-caffeoylquinic acid (13) and 1,5-di-O-caffeoylquinic acid (14).Among them,compounds 5-10 and 12-14 were isolated from the fruits of Akebiae quinata for the first time.

Key words: Akebiae quinata, chemical constituents, non-triterpenoid compounds, caffeoylquinic acid, structure identification

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