Abstract: Tripterygium wilfordii containing many active components had a long history of clinical application in traditional Chinese medicine for its extensive pharmacological activities.Alkaloids,the main active components of T. wilfordii,possessed many pharmacological activities,such as immunosuppression,anti-inflammation,analgesia,anti-tumor,anti-HIV,insecticidal,neuroprotection and so on.So far,more than 160 various alkaloids had been isolated from T. wilfordii.In this paper,the research progress of alkaloids from T. wilfordii were summarized in order to support the further research and development of these components.

Key words: Tripterygium wilfordii, alkaloid, bioactivity