Abstract: Micromonospora was a rare actinomycete and widely distributed in the soil,sea,animals and plants.Its metabolites not only had anti-microbial,anti-tumor,anti-HIV and other biological activities,but also had novel and diverse chemical structures.Herein,we briefly reviewed the chemical structure and biological activity of natural products from the genus Micromonospora within the recent years,by which to lay a foundation for future development and application of natural products from Micromonospora.

Key words: rare actinomycetes, micromonospora, secondary metabolite, bioactivity, chemical structure