NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2024, Vol. 36 ›› Issue (增刊2): 131-142.

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Research progress on chemical compositions and pharmacological effects of Fritillariae Pallidiflorae Bulbus

DONG Yuan-qiu,LEI Ting,ZHANG Jin-qiang*   

  1. Guizhou University of Traditional Chinese Medicine,Guiyang Guiyang 550025,China
  • Online:2024-12-09 Published:2024-12-09

Abstract:

Fritillariae Pallidiflorae Bulbus is the dried bulb of Fritillaria walujewii or F. pallidiflora,which is mainly produced in Xinjiang.It has the effect of clearing heat and moisturizing the lung,resolving phlegm and relieving cough.It is often used in the clinical treatment of lung heat dry cough,dry cough with less phlegm,Yin deficiency and cough with blood and other symptoms.There are a variety of active ingredients in the Fritillariae Pallidiflorae Bulbus,108 chemical compounds,including 36 alkaloids,16 steroidal saponins,5 steroidal glycoalkaloids,7 polysaccharides,4 coumarins,4 nucleosides,21 organic acids and esters,and 15 other compounds were identified.These ingredients has expectorant,and asthma,cough,anti-tumor,antioxidant,antibacterial,anti-inflammatory,nerve protection and so on the many kinds of pharmacological activities.This article reviews the research status of chemical components and pharmacological effects of Fritillariae Pallidiflorae Bulbus,in order to provide reference for the understanding and research of chemical components and pharmacological effects of Fritillariae Pallidiflorae Bulbus,and provide basis for the in-depth development and utilization of medicinal materials.

Key words: Fritillariae Pallidiflorae Bulbus, traditional Chinese medicine, chemical constituents, pharmacological effects, Dispel phlegm and relieve cough

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