NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2024, Vol. 36 ›› Issue (增刊2): 143-150.

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Development and application of Angelica sinensis polysaccharides:a review

YIN Kai1,2,SHI Yu-cun1,2,HOU Xiao-ying1,2,GAO Fan1,4,WU Guo-tai2,3,4*   

  1. 1School of Pharmacy,Gansu University of Traditional Chinese Medicine;2Longyao Industry Innovation Research Institute;
    3Collaborative Innovation Center for Northwest Chinese and Tibetan Medicine;4Gansu Provincial Key Laboratory of  Pharmacology and Toxicology of Traditional Chinese Medicine,Lanzhou 730000,China
  • Online:2024-12-09 Published:2024-12-09

Abstract:

Angelica sinensis is a frequently used traditional Chinese medicine with traditional medicinal and food ingredients,and A. sinensis polysaccharide is one of its effective components,which has a wide range of pharmacological effects such as blood tonicity,anti-inflammation,and antioxidant.With the continuous development of extraction and purification of natural polysaccharides from traditional Chinese medicine and structural analysis technologies,the number of A. sinensis polysaccharides,their composition and chemical structure have been constantly improved,which reflects the characteristics of biodegrad ability,lower difficulty of structural modification,natural liver targeted and so on,and it has a brilliant prospect for drug carriers.In this paper,the new developments in the structural analysis,extraction and purification,and expanded application of A. sinensis polysaccharides are summarised to provide reference for the further development and utilisation of A. sinensis polysaccharides.

Key words: Angelica sinensis polysaccharides, structural elucidation, extraction and purification, chemical modification, drug carriers

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