Chemical Constituents of an Endophytic Fungus Aspergillus flavipes AIL8 obtained from Mangrove Acanthus ilicifolius

doi:10.16333/j.1001-6880.2016.6.008

Abstract

Abstract: In this study,the chemical constituents of an endophytic fungus Aspergillus flavipes AIL8 obtained from mangrove Acanthus ilicifolius were isolated and purified by column chromatography on silica gel,Sephadex LH-20 and semi-preparative HPLC.The structures of the isolated compounds were determined on the basis of spectroscopic analysis and comparison with literature data.Six compounds were identified as 4-hydroxy-3-methoxy-5-((2E,6E)-3,7,11-trimethyldodeca -2,6,10-trien-1-yl)benzoic acid (1),aromatic lactone derivative (2),2,3-dihydroxypropyl decanoate (3),brassicasterol (4),7,22(E)-ergostadiene-3β,5α,6β-triol (5) and ergosterol-6,22-diene-5α,8α-epidioxy-3β-ol (6).All the 6 compounds were isolated from this strain for the first time,in which compound 1 was a new natural product.

Key words: Acanthus ilicifolius, endophytic fungus, Aspergillus flavipes AIL8

CLC Number:

O629.9

WANG Bin1,BAI Zhi-qiang2,LIN Xiu-ping2,YANG Bin2,ZHOU Xue-feng2,LIU Yong-hong2*. Chemical Constituents of an Endophytic Fungus Aspergillus flavipes AIL8 obtained from Mangrove Acanthus ilicifolius[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(6): 860-863.

[1]	ZENG Qing-ting, YUAN Tao. Secondary metabolites of endophyte Paraconiothyrium sp.YLHJ01 from Artemisia selengensis [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2023, 35(5): 781-786.
[2]	TAN Hui, PI Li, YANG Xiao-long, AN Ting, GUO Xu-dong, LIU Yan-ping, WEN Huai-xiu. Isolation and indentification of an endophytic fungus X-396 from Hypecoum leptocarpum Hook.f.et Thoms.and analysis on fat-soluble components of its fermentation [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2023, 35(3): 420-426.
[3]	XU Xiao-tian, JI Ling-bo, DUAN Xiao-qun, WANG Yu-hui. Study on the secondary metabolites of endophytic fungus Aspergillus sp. from Aspongopus chinensis and their antimicrobial activity [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2022, 34(8): 1332-1337.
[4]	CHEN Zan-hong, ZHU Jing-lin, LIN Ling-yin, GUO Si-yu, HUANG Mei-ying, XU Wen-yan, HUANG Hong-bo, TAO Yi-wen. Dimeric naphthopyrones produced by a mangrove endophytic fungus Aspergillus fumigatus SAS10 [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2022, 34(6): 967-974.
[5]	ZENG Hui-ting, YE Lin, YI Wei-ting, CHEN Jia-yi, XU Shan-shan, ZHAO Li-juan, ZENG Xi, YUAN Tao. Study on secondary metabolites of endophytic fungus Talaromyces sp. from Uncaria rhynchophylla [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2022, 34(10): 1707-1712.
[6]	LIANG Wei-zhong, XIAO Yi-wen, ZHANG Wen-hui, WANG Ya, GAO Bo-liang, ZHU Du. Isolation of secondary metabolites and antimicrobial activity of endophytic fungus Sarocladium oryzae L99 [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(增刊1): 35-42.
[7]	JU Feng, LUO Fan, FENG Dan, GUO Da-le, REN Bo, DENG Yun. Study on the chemical constituents of Penicillium crustosum,an endophytic fungus from Ophiocordyceps sinensis [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(7): 1147-1155.
[8]	HU Xiao-feng, CHAI Hai-quan, JIA Lin-chuan, SHAO Lu, LIU Xiao-xiao, CHEN Ye. Antitumor secondary metabolites of an endophytic fungus Aspergillus terreus TZS-201607 from Pseudostellaria heterophylla [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(7): 1156-1164.
[9]	ZHANG Jie, LIU Hong-xin, LIU Zhao-ming, LI Sai-ni, CHEN Yu-chan, ZHANG Wei-min , GUO Bo-hong . Secondary metabolites of endophytic fungus Letendraea helminthicola derived from Amomum villosum [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(5): 773-778.
[10]	ZHANG Wen-hui, XIAO Yi-wen, LIANG Wei-zhong, WANG Ya, GAO Bo-liang, ZHU Du. Isolation of secondary metabolites from endophytic fungus Chaetomium globosum S108 and its antimelanoma activity [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(11): 1854-1859.
[11]	XIA Gui-ru, SONG Wen-min, ZHANG Zhi-yan, YANG Tian-he, GUO Zhi-yong, ZHANG Xue-qing. Study on the secondary metabolites and their inhibitory activity against α-glucosidase from the endophytic fungus Phomopsis prunorum isolated from Hypericum ascyron L. [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2021, 33(10): 1707-1712.
[12]	PAN Rui, YU Rong-lu, LI Ming-zhu, WANG Hong, ZHANG Hua-wei. Secondary metabolites of an endophytic fungus D from Edgeworthia chrysantha [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2020, 32(增刊1): 73-76.
[13]	WANG Jun-li, WANG Long, OUYANG Hu, JIAO Song-lin, REN Jian-guo. Study on the antioxidant activity of the metabolites of endophytic fungus NSZJ-1 from Pseudostellaria heterophylla [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2020, 32(11): 1920-1927.
[14]	ZHENG Hao1,2,MEI Wen-li2,CAI Cai-hong2，GAI Cui-juan2,DAI Hao-fu2,TAN Zhi-qiong1 ,CHEN Hui-qin2 . Study on the secondary metabolites and their bioactivities of the endophytic fungus Colletotrichum sp. HK-08 from the leaves of Nerium indicum [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2020, 32(1): 75-80.
[15]	LIU Cong-bin1,LIU Hai-tao1,YANG Jai-sing2,LIU Jin-song1,WANG Gang1,WANG Guo-kai1 . Secondary metabolites of endophytic fungus Fusarium tricinctum from Ningguo Peucedanum praeruptorum* Dunn. [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2019, 31(9): 1580-1584.

Chemical Constituents of an Endophytic Fungus Aspergillus flavipes AIL8 obtained from Mangrove Acanthus ilicifolius

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments