Abstract: The purpose of this study was to explore the influence of pH,concentration and curing time on the adhesive strength of soybean protein isolate (SPI) onto porcine bones.SPI adhesive was used to bond porcine bones and its bonding performance parameters were optimized through orthogonal experiments.The results of single factor test showed that SPI concentration,pH (at 6.5 and 8.5) and curing time (at 12 h and 36 h) had significant effects on the adhesive strength (P<0.05).The results of orthogonal experiments indicated that the optimal bonding performance of the adhesive was obtained at SPI concentration of 10%,pH of 6.5 and curing time of 48 h.Under the optimal condition the bonding strength of the SPI adhesive was 380 KPa,suggesting that SPI has a potential to be utilized as an adhesive in medical fields.

Key words: soybean protein isolate, bone, adhesive strength