NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (2): 240-244.doi: 10.16333/j.1001-6880.2017.2.010

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Isolation,Purification and Structural Identification of Cyclosporine Analogues from Fermentation Broth of Strain Fusarium solani sp.FIM116

YANG Huang-jian#,WANG De-sen#,ZHANG Zhu-lan*,TANG Wen-li,REN Lin-ying,QIU Guan-rong,LIAN Yun-yang*   

  1. Fujian Key Laboratory of Screening for Novel Microbial Products,Fujian Institute of Microbiology,Fuzhou 350007,China
  • Online:2017-02-28 Published:2017-03-07

Abstract: Two cyclosporine analogues were isolated and purified by solvent extraction,silica gel chromatography,reversion phase chromatography and other ways from the fermentation broth of Fusarium solani sp.FIM116.Their structures were identified as cyclosporine G and cyclosporine T by physic-chemical properties and spectroscopic data.

Key words: Fusarium solani, cyclosporine G, cyclosporine T, isolation and purification, structural identification

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