NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (2): 264-267.doi: 10.16333/j.1001-6880.2017.2.014

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Composition and Antitumor Activities of Essential Oil from Murdannia bracteata

CHEN Xin-yin1,XU Liang-kui2,YANG Yan-jun3,ZENG Qing-qian3,FANG Chun-sheng2,JIAO Hao-yan3,NIE Yang2,3*   

  1. 1 School of Engineering,Sun Yat-Sen University,Guangzhou 510006,China;2Guangdong Food and Drug Vocational College；3Traditional Chinese Medical Institute of Guangdong Province,Guangzhou 510520,China
  • Online:2017-02-28 Published:2017-03-07

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Abstract: The essential oil from Murdannia bracteata was extracted by steam-stilling and analyzed by GC-MS.Fifty-one chromatographic peaks were detected and thirty-nine compounds were identified,which were 83.48% of the essential oil.The major components were n-hexadecanoic acid (17.57%),cubenol (10.62%),2pentadecanone (8.50%) and 1,1,10-trimethy-2-hydroxyl-6,9-epidioxydecalin (6.57%).The essential oil showed significant antitumor activities against A549,PC-3,SGC-7901 and Hep G2 cells,especially against SGC-7901 and Hep G2 cell lines (IC50 value of 35.01 μg/mL and 22.43 μg/mL,respectively).The essential oil from M.bracteata contained various antitumor constituent.The results of this study provided scientific reference for further utilization of M.bracteata.

Key words: Murdannia bracteata, essential oil, GC-MS, antitumor activity

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