NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (6): 959-962. doi: 10.16333/j.1001-6880.2017.6.010

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Secondary Metabolites from South China Sea Deep-water-derived Fungus Exophiala sp.SCSIO 05791

LUO Xiao-wei1,2,LIN Xiu-ping1,SALENDRA Limbadri1,2,PANG Xiao-yan1,2,DAI Yu1,2,LIU Yong-hong1,3*   

  1. 1 GuangdongKey Laboratory of Marine Materia Medica,South China Sea Institute of Oceanology, Chinese Academy of Sciences,Guangzhou 510301,China; 2University of Chinese Academy of Sciences,Beijing 100049,China; 3 South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangzhou 510275,China
  • Online:2017-06-30 Published:2017-07-06

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Abstract: The secondary metabolites of Exophiala sp.SCSIO 05791,a fungus isolated from South China Sea 500 m depth water,were investigated.Eight compounds were obtained from the rice static fermentation products,which were purified by comprehensive chromatography methods of silica gel column,Sephadex LH-20, Ostade-cylsilane (ODS),and semi-preparative HPLC and their structures were elucidated by means of physical and chemical properties,spectroscopic analysis,and comparison with the reported literatures,which were stephacidin A(1),indole-3-acetic acid (2),cyclo(D)-Pro-(D)-Phe(3), trans-ferulic acid(4), cis-ferulic acid (5), 2-(acetylamino)-phenol (6),anthranilic acid(7) and 4-hydroxyphthalide (8).Compounds 1-8 were all obtained from genus Exophiala for the first time.

Key words: South China Sea, marine fungi, secondary metabolites, Exophiala sp.