NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2017, Vol. 29 ›› Issue (增刊1): 133-137. doi: 10.16333/j.1001-6880.2017.S.027

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Sanguisorba Tannins and Saponins Rise White Blood Cells based on the Effect of Proliferation of Hematopoietic Cells

XIONG Yong-ai1,WANG Fang2,YANG Ming2*   

  1. 1Pharmaceutical College,Zunyi Medical University,Zunyi 563003,China;2 Jiangxi University of Traditional Chinese Medicine,Key Lab.of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Nanchang 330004,China
  • Online:2017-08-02 Published:2017-08-02

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Abstract: To study the sanguisorba tannins and saponins rising white blood cells based on the effect of proliferation of hematopoietic cells.Mice HSPCs and granulocyte were isolated and purified,after be intervented by Sanguisorba Tannins and Saponins,the proliferation of HSPCs and Granulocyte were observed.HSPCs were main target cells of Sanguisorba Tannins,it might be to increase WBC via accelerating the proliferation and differentiation of HSPCs,further promoting myeloid stem cell numbers.While the Granulocyte were main target cells of Sanguisorba Saponins.It it might be to increase WBC via accelerating the proliferation and differentiation of myeloid stem cells into Granulocyte.Sanguisorba rised white blood cell could be a combined effect of sanguisorba tannins and saponins acting on HSPCs and Granulocyte.

Key words: sanguisorba tannins, sanguisorba saponins, HSPCs, granulocytes, proliferation