Effects of Polygonatum odoratum Polysaccharide on Anti-Fatigue in Mice

doi:10.16333/j.1001-6880.2018.7.018

Abstract

Abstract: To investigate the antioxidant and antifatigue effects of Polygonatum odoratum polysaccharide (POP).The POP was extracted by water extraction,alcohol precipitation,Acetone elution and trichloroacetic acid precipitation.A weight loaded swimming model and a free swimming model of mice were established.Meanwhile the mice were given different doses of POP.After loaded-swimming and free swimming for 30 minutes,Lactate dehydrogenase (LDH),lactic acid (LD),creatine phosphate kinase (CK),blood urea nitrogen (BUN),superoxide dismutase (SOD),catalase (CAT),(glutathione) GSH and malondialdehyde (MDA) were measured.The results indicated that POP can significantly prolong the loaded swimming time,increase the contents of blood glucose,muscle glucose,SOD,CAT and GSH i,and decrease the levels of LDH,LD,CK,BUN and MDA.

Key words: Polygonatum odoratum, polysaccharide, anti-fatigue

CLC Number:

R285.5

NIU You-ya1,2. Effects of Polygonatum odoratum Polysaccharide on Anti-Fatigue in Mice[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2018, 30(7): 1202-1207.

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Effects of Polygonatum odoratum Polysaccharide on Anti-Fatigue in Mice

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