NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2019, Vol. 31 ›› Issue (1): 81-86.doi: 10.16333/j.1001-6880.2019.1.013

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Chemical constituents of the water extracts of Averrhoa carambola L.root and their biological activities

LIAO Peng-ying1*, ZHOU Zhong-yu2,3, CHEN Ying-ran1, CHEN Hui-ping1, PAN Wei-gao1, YANG Xiao-mei1, HUANG Zhi-xiang1   

  1. 1Guangxi University of Chinese Medicine,Nanning 530001,China; 2Key Laboratory of Plant Resources Conservation and Sustainable Utilization,South China
    Botanical Garden,Chinese Academy of Sciences; 3Guangdong Provincial Key Laboratory of Applied Botany,South China Botanical Garden,Chinese Academy of Sciences,Guangzhou 510650,China
  • Online:2019-01-28 Published:2019-01-28

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Abstract: To further investigate the antidiabetic constituents from the root of Averrhoa carambola L.,nine compounds were isolated from the water extracts by series column chromatographies and their structures were identified as prismaconnatoside (1),tarennanosides A (2),(+)-catechin (3),fernandoside (4),7a-［(β-glucopyranosyl)oxy］-lyoniresinol (5),(+)-lyoniresinol 3α-O-β-D-glucopyranoside (6),(-)-lyoniresinol 3α-O-β-D-glucopyranoside (7),(-)-5’-methoxy-isolariciresinol 3α-O-β-D-glucopyranoside (8),and n-octane (9).Compounds 1,2,4,and 5 were isolated from Averrhoa carambola for the first time.Compound 3 was isolated from the root part of Averrhoa carambola for the first time.Some compounds were assayed for the α-glucosidase and DPP-IV inhibitory activities in vitro.Compound 1 showed α-glucosidase inhibitory activity.

Key words: root part of Averrhoa carambola L., chemical constituents, purification, structure elucidation, α-glucosidase inhibitory activity

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