Abstract: In order to identify Saposhnikoviae Radix and its counterfeit,the content of four chromogen ketones in them were analyzed by high performance liquid chromatography (HPLC),and their chemical fingerprints were established.The results of similarity analysis showed that the similarity between the samples was 0.087-0.997,which indicated that the difference between Saposhnikoviae Radix and its adulterants was great.On the basis of this,the systematic cluster analysis and principal component analysis were carried out with four chromophotoketones as provariables.The results showed that the HPLC method could be used to identify the authentic and the counterfeit of Saposhnikoviae Radix.The results revealed the internal relationship between the chemical quantitative indexes of Saposhnikoviae Radix and its counterfeit,and provided a new idea for the objective comprehensive evaluation of the quality and authenticity of Saposhnikoviae medicinal materials.

Key words: Saposhnikoviae Radix, HPLC, stoichiometry, distinguish