Abstract: Fucoidans were heterogeneous sulfated polysaccharides with abundant of fucose and sulfate groups,they can be extracted from brown algae and marine invertebrates. They were widely used in the fields of medicine and food due to their numerous biological functions. The purpose of this paper is to summarize the preparation and structural characteristics of fucoidans,and their potential protective effects in cardio-cerebrovascular diseases based on their biological functions such as antithrombosis,anticoagulation,antiinflammation,lipid-lowering,immunoregulation and antioxidation.

Key words: fucoidan, preparation, structural characteristic, biological function, PCSK9