NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2020, Vol. 32 ›› Issue (12): 2132-2141. doi: 10.16333/j.1001-6880.2020.12.019

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Research progress on the mechanism of Chinese medicine against colorectal cancer

LI Bian-li1,2,3,4,CHEN Hua-guo1,2,3,ZHAO Chao1,2,3,ZHOU Xin1,2,3*   

  1. 1Guizhou Normal University Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment;
    2Guizhou Normal University Collaborative Innovation Center for Karst Mountain Ecological Environment Protection and Resource Utilization (Project of Education Department of Guizhou Province);3Guizhou Normal University Guizhou Provincial Laboratory of Drug Quality Control and Evaluation Technology,Guiyang 550001,China;4Guizhou University of Traditional Chinese Medicine,Guiyang 550002,China

  • Online:2020-12-28 Published:2020-12-25

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Abstract:

Colorectal cancer is one of the most common digestive tract cancers with high morbidity and mortality,which seriously threaten human's normal life.With the development in recent years,traditional Chinese medicine has become an effective method for the treatment of colorectal cancer.This paper systematically summarized the anti-colorectal cancer mechanism of Chinese herbal formula,extract and monomer compound,such as inducing cell apoptosis,inhibiting cancer cell proliferation and blocking cell cycle,etc.Furthermore,the research status of traditional Chinese medicine in the treatment of colorectal cancer was analyzed,which could provide reference for the development of new anti-colorectal traditional Chinese medicine.

Key words: colorectal cancer, traditional Chinese medicine, mechanism, research status 

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