NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2021, Vol. 33 ›› Issue (3): 521-533. doi: 10.16333/j.1001-6880.2021.3.020

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New advances in research on anti-ovarian cancer effect and mechanism of traditional Chinese medicine

WEN Min1,2,3,4,ZHOU Xin1,2,3,4,ZHAO Chao1,2,3,4,GONG Xiao-jian1,2,3,4*   

  1. 1Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University;2Collaborative Innovation Center for Karst Mountain Ecological Environmental Protection and Resource Utilization (Project of Education Department of Guizhou Province),Guizhou Normal University;3Guizhou Engineering Laboratory for Quality Control ＆ Evaluation Technology of Medicine,Guizhou Normal University;4 Research Center for Quality Control of Natural Medicine,Guizhou Normal University,Guiyang 550001,China

  • Online:2021-03-28 Published:2021-04-01

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Abstract:

Ovarian cancer is one of the common malignant tumors of female reproductive organs,which seriously threatens female reproductive health.The treatment of ovarian cancer with traditional Chinese medicine has the characteristics of multi-target,multi-channel and small side effects,which has become the research focus of scholars at home and abroad in recent years.This paper systematically summarized the anti-ovarian cancer activity and mechanism of Chinese herbal formula,plant medicine (polysaccharides,flavonoids,alkaloids,phenols, terpenes,quinones,saponins,esters,volatile oil,ethers),animal medicine and mineral medicine,furthermore,the structure-activity relationship of the effective ingredients of traditional Chinese medicine against ovarian cancer was preliminarily analyzed,which could provide a reference for the in-depth research and application of anti-ovarian cancer drugs.

Key words: ovarian cancer, traditional Chinese medicine, activity, mechanism of action, structure-activity relationship

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